Table of Contents Author Guidelines Submit a Manuscript
International Journal of Antennas and Propagation
Volume 2013 (2013), Article ID 309703, 11 pages
http://dx.doi.org/10.1155/2013/309703
Research Article

A Feasibility Study for Microwave Breast Cancer Detection Using Contrast-Agent-Loaded Bacterial Microbots

1Department of Electrical and Electronic Engineering, South University of Science and Technology of China, Shenzhen 518055, China
2School of Natural and Mathematical Sciences, King’s College London, London WC2R 2LS, UK
3Department of Computer Engineering, Ecole Polytechnique de Montreal, Montreal, Canada H3T 1J4

Received 25 June 2013; Accepted 24 September 2013

Academic Editor: Soon Yim Tan

Copyright © 2013 Yifan Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. N. K. Nikolova, “Microwave imaging for breast cancer,” IEEE Microwave Magazine, vol. 12, no. 7, pp. 78–94, 2011. View at Publisher · View at Google Scholar · View at Scopus
  2. M. Lazebnik, D. Popovic, L. McCartney et al., “A large-scale study of the ultrawideband microwave dielectric properties of normal, benign and malignant breast tissues obtained from cancer surgeries,” Physics in Medicine and Biology, vol. 52, no. 20, pp. 6093–6115, 2007. View at Publisher · View at Google Scholar · View at Scopus
  3. A. Mashal, B. Sitharaman, X. Li et al., “Toward carbon-nanotube-based theranostic agents for microwave detection and treatment of breast cancer: enhanced dielectric and heating response of tissue-mimicking materials,” IEEE Transactions on Biomedical Engineering, vol. 57, no. 8, pp. 1831–1834, 2010. View at Publisher · View at Google Scholar · View at Scopus
  4. S. Semenov, N. Pham, and S. Egot-Lemaire, “Ferroelectric nanoparticles for contrast enhancement microwave tomography: feasibility assessment for detection of lung cancer,” in Proceedings of the World Congress on Medical Physics and Biomedical Engineering, pp. 311–313, Munich, Germany, September 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. A. I. Minchinton and I. F. Tannock, “Drug penetration in solid tumours,” Nature Reviews Cancer, vol. 6, pp. 583–592, 2006. View at Google Scholar
  6. S. Martel, M. Mohammadi, O. Felfoul, Z. L. Zhao Lu, and P. Pouponneau, “Flagellated magnetotactic bacteria as controlled MRI-trackable propulsion and steering systems for medical nanorobots operating in the human microvasculature,” International Journal of Robotics Research, vol. 28, no. 4, pp. 571–582, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. N. Mokrani, O. Felfoul, F. A. Zarreh et al., “Magnetotactic bacteria penetration into multicellular tumor spheroids for targeted therapy,” in Proceedings of the 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC '10), pp. 4371–4374, Buenos Aires, Argentina, September 2010. View at Publisher · View at Google Scholar · View at Scopus
  8. J. D. Shea, P. Kosmas et al., “Contrast-enhanced microwave imaging of breast tumors: a computational study using 3D realistic numerical phantoms,” Inverse Problems, vol. 26, Article ID 074009, 2010. View at Google Scholar
  9. Y. Chen, I. J. Craddock, and P. Kosmas, “Feasibility study of lesion classification via contrast-agent-aided UWB breast imaging,” IEEE Transactions on Biomedical Engineering, vol. 57, no. 5, pp. 1003–1007, 2010. View at Publisher · View at Google Scholar · View at Scopus
  10. P. Kosmas and Y. Chen, “Possibilities for microwave breast tumor sensing via contrast-agent-loaded nanorobots,” in Proceedings of the 6th European Conference on Antennas and Propagation (EUCAP '12), Prague, Czech Republic, March 2012.
  11. Y. Chen and P. Kosmas, “Detection and localization of tissue malignancy using contrast-enhanced microwave imaging: exploring information theoretic criteria,” IEEE Transactions on Biomedical Engineering, vol. 59, no. 3, pp. 766–776, 2012. View at Publisher · View at Google Scholar · View at Scopus
  12. Y. Chen and P. Kosmas, “Microwave breast tumor sensing and targeting using multiswarm contrast-agent-loaded bacterial nanorobots,” in Proceedings of the International Conference on Electromagnetics in Advanced Applications (ICEAA '12), Cape Town, South Africa, September 2012.
  13. E. Zastrow, S. K. Davis, M. Lazebnik, F. Kelcz, B. D. Van Veen, and S. C. Hagness, “Development of anatomically realistic numerical breast phantoms with accurate dielectric properties for modeling microwave interactions with the human breast,” IEEE Transactions on Biomedical Engineering, vol. 55, pp. 2792–2800, 2008. View at Google Scholar
  14. S. Martel, O. Felfoul, J.-B. Mathieu et al., “MRI-based medical nanorobotic platform for the control of magnetic nanoparticles and flagellated bacteria for target interventions in human capillaries,” International Journal of Robotics Research, vol. 28, no. 9, pp. 1169–1182, 2009. View at Publisher · View at Google Scholar · View at Scopus
  15. S. Martel, O. Felfoul, M. Mohammadi, and J. B. Mathieu, “Interventional procedure based on nanorobots propelled and steered by flagellated magnetotactic bacteria for direct targeting of tumors in the human body (IEEE EMBC '08),” in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Vancouver, Canada, August 2008.
  16. S. Martel, O. Felfoul, and M. Mohammadi, “Flagellated bacterial nanorobots for medical interventions in the human body,” in Proceedings of the 2nd Biennial IEEE/RAS-EMBS International Conference on Biomedical Robotics and Biomechatronics (BioRob '08), pp. 264–269, October 2008. View at Publisher · View at Google Scholar · View at Scopus
  17. C. C. Tremblay, J. Jean, L. Marchand et al., “Robotic platform for real-time tracking of a single fast swimming bacterium,” in Proceedings of the International Symposium on Optomechatronic Technologies (ISOT '10), Toronto, Canada, October 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. R. Folberg, M. J. C. Hendrix, and A. J. Maniotis, “Vasculogenic mimicry and tumor angiogenesis,” The American Journal of Pathology, vol. 156, no. 2, pp. 361–381, 2000. View at Google Scholar · View at Scopus
  19. Y. Chen, E. Gunawan, K. S. Low, S.-C. Wang, C. B. Soh, and L. L. Thi, “Time of arrival data fusion method for two-dimensional ultrawideband breast cancer detection,” IEEE Transactions on Antennas and Propagation, vol. 55, no. 10, pp. 2852–2865, 2007. View at Publisher · View at Google Scholar · View at Scopus
  20. W. Wei, X. Jin-Yu, and Z. Zhong-Liang, “A new NLOS error mitigation algorithm in location estimation,” IEEE Transactions on Vehicular Technology, vol. 54, no. 6, pp. 2048–2053, 2005. View at Publisher · View at Google Scholar · View at Scopus