Research Article

A Comparative Analysis of Biomarker Expression and Molecular Subtypes of Pure Ductal Carcinoma In Situ and Invasive Breast Carcinoma by Image Analysis: Relationship of the Subtypes with Histologic Grade, Ki67, p53 Overexpression, and DNA Ploidy

Table 1

Comparison of clinicopathologic parameters in pDCIS versus IBCA.

VariablespDCIS ( 𝑛 = 1 1 8 )IBCA ( 𝑛 = 1 0 0 ) 𝑃 value*

Age (mean)61.4 ± 1.0361.8 ± 0.87NS
Tumor size (mean)2.95 ± 0.233.37 ± 0.32NS
Tumor grade
Low9 (7.6%)11 (11%)NS
Intermediate46 (38.9%)49 (49%)NS
High63 (53.3%)40 (40%)0.0570

*Chi-square test.
NS: not significant.