International Journal of Breast Cancer / 2011 / Article / Tab 2

Research Article

A Comparative Analysis of Biomarker Expression and Molecular Subtypes of Pure Ductal Carcinoma In Situ and Invasive Breast Carcinoma by Image Analysis: Relationship of the Subtypes with Histologic Grade, Ki67, p53 Overexpression, and DNA Ploidy

Table 2

A comparison of biomarker expression in pDCIS versus IBCA.

Tumor biomarkerspDCISIBCA 𝑃 value*

ER+97 (82.2%)66 (66%) 𝑃 = 0 . 0 0 7 7
ERβˆ’21 (17.7%)34 (34%)
PR+81 (68.6%)50 (50%) 𝑃 = 0 . 0 0 5 7
PRβˆ’37 (31.3%)50 (50%)
HER2+ (FISH)36 (30.5%)23 (23%) 𝑃 = 0 . 2 8 5 9
HER2βˆ’82 (69.4%)74 (74%)
Ki67 > 10%78 (66.1%)84 (84%) 𝑃 = 0 . 0 0 3 0
Ki67 < 10%40 (33.8%)16 (16%)
P53 >10%27 (22.8%)26 (26%) 𝑃 = 0 . 6 3 6 3

P53 <10%91 (77.1%)74 (74%)
Total118100

*Chi-square test; 𝑃 < 0 . 0 5 is significant.

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