International Journal of Breast Cancer / 2011 / Article / Tab 4

Research Article

A Comparative Analysis of Biomarker Expression and Molecular Subtypes of Pure Ductal Carcinoma In Situ and Invasive Breast Carcinoma by Image Analysis: Relationship of the Subtypes with Histologic Grade, Ki67, p53 Overexpression, and DNA Ploidy

Table 4

Relationship of tumor grade with quantitative biomarker expression in IBCA.

VariablesIBCA grade 𝑃 value (ANOVA)

gradeGrade 1 (11)Grade 2 (49)Grade 3 (40)

ER-score (%)84.4 ± 8.8075.3 ± 5.1829.65 ± 6.69 𝑃 < 0 . 0 0 0 1
PR-score (%)49.1 ± 13.635.16 ± 5.3414.30 ± 4.71 𝑃 = 0 . 0 0 5 1
Ki67 (%)14.7 ± 2.4029.71 ± 3.5561.2 ± 4.17 𝑃 < 0 . 0 0 0 1
P53 (%)11.8 ± 8.2310.39 ± 3.2627.95 ± 6.26 𝑃 = 0 . 0 1 8 0

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