A Comparative Analysis of Biomarker Expression and Molecular Subtypes of Pure Ductal Carcinoma In Situ and Invasive Breast Carcinoma by Image Analysis: Relationship of the Subtypes with Histologic Grade, Ki67, p53 Overexpression, and DNA Ploidy

Table 5

The prevalence of the molecular subtypes in pDCIS versus IBCA by IHC.

Molecular subtypes	Pure DCIS	IBCA	𝑃 value
Luminal-A	44 (37.3%)	21 (21%)	0.0113
Luminal-B	31 (26.3%)	30 (30%)	0.5490
HER2*	36 (31%)	23 (23%)	0.2252
Triple negative	7 (6%)	26 (26%)	<0.0001
Total	118	100

*Luminal-HER2 and HER2 subtypes are combined together as one group.