Role of CEACAM1, ECM, and Mesenchymal Stem Cells in an Orthotopic Model of Human Breast Cancer
Figure 1
Comparison of human mammary xenograft formation by MCF-7 and MCF7/CEACAM1 in either humanized mammary fat pad or nascent mammary fat pad in NOD/SCID mice. Gross pictures (left panels) of human xenografts and corresponding H and E stained sections (right panels) of MCF7 xenografts (a) in humanized mammary fat pads or (b) MCF7 xenografts in nascent mouse mammary fat pads) or (c) MCF7/CEACAM1 xenografts in humanized mammary fat pads or (d) MCF7/CEACAM1 xenografts in nascent mouse mammary fat pads. Magnification 200x.
