Role of CEACAM1, ECM, and Mesenchymal Stem Cells in an Orthotopic Model of Human Breast Cancer
Figure 3
Effect of ECM and stromal cells on growth and differentiation of MCF7/CEACAM1 xenografts. Gross pictures of human xenografts (left panels) and corresponding H AND E stained sections of xenografts (right panels) containing MCF7/CEACAM1 cells in mouse mammary fat pad with (a) hTert/MSC and no ECM, (b) ECM (Matrigel alone) and no stromal cells, and (c) ECM ( Collagen 1 and Matrigel 3 : 1 ratio) and no stromal cells. Magnification 200x.