Role of CEACAM1, ECM, and Mesenchymal Stem Cells in an Orthotopic Model of Human Breast Cancer
Figure 6
Effect of physiological status of the mammary gland on growth and differentiation of xenografts. MCF7/CEACAM1 cells along with hTert/MSC (1 : 1 ratio) in Matrigel were implanted into the inguinal mammary fat pads of eight-week-old female NOD/SCID mice and immediately mated to induce the pregnancy to change the physiological status of mammary gland. After weaning of pups, (a) xenografts were collected and (b) H and E staining performed on sections from xenografts. Magnification 200x.
