Secretory Carcinoma of Male Breast: Case Report and Review of the Literature

Table 1

Data on 18 males with secretory breast cancer [3].

Author	Year	Age	Duration of symptoms	Size (cm)	Axillary status	Treatment	Hormone receptors	ETV6-NTRK3	Followup
Simpson and Barson [5]	1969	5	ND	ND	− (clinical)	LE	NE	NE	NED 4 y
Tavassoli and Norris [10]	1980	9	ND	ND	− (clinical)	LE	NE	NE	NED 1.75 y
Karl et al. [12]	1985	3	1 mo	1.5	+ (1/4)	SM+ALNS	NE	NE	ND
Roth et al. [13]	1988	23	21 years	2.0	− (0/21)	MRM	NE	NE	NED 4 y
Krausz et al. [14]	1989	24	Many years	4.0	ND	SM + RT (axilla)	NE	NE	DOD 20 y
Serour et al. [15]	1992	17	4 years	1.5	− (0/3)	WLE + ALND	ER − PR+	NE	NED 5 y
Lamovec and Bracko [16]	1994	20	ND	1.2	− (0/?)	MRM	ER+ PR+	NE	NED 1 y
Pohar-Marinsek and Golouh [6]	1994	20	6-7 years	1.2	− (clinical)	SM	ER+ PR+	NE	NED 6 m
Kuwabara et al. [17]	1988	66	3 years	3.0	+ (2/?)	MRM	ER − PR+	NE	NED 8 m
Vesoulis and Kashkari [18]	1998	33	10 years	1.5	ND	MRM	ER+ PR+	NE	ND
Kameyama et al. [19]	1998	50	ND	3.0	− (0/?)	MRM	ER+	NE	ND
Chevallier et al. [20]	1999	9	14 m	2.0	− (0/?)	LE + ALND	ER − PR−	NE	NED 45 m
Yildirim et al. [21]	1999	11	1 year	1.5	+ (1/18)	MRT + CT+ RT	ER−	NE	NED 12 m
Bhagwandeen and Fenton [22]	1999-2000	9	1 m	1.2	− (0/15)	MRM	ER − PR−	NE	NED 20 m
De Bree et al. [11]	2001	17	2 years	2.0	− (0–14)	MRM	ER − PR−	NE	NED 9 m
Niveditha et al. [23]	2004	19	2 years		ND	WLE	ER − PR−	NE	ND
Grabellus et al. [24]	2005	46 male-female transexual	ND	4.0	ND	LE	ER − PR−	PRESENT	ND
McDivitt and Stewart [2]	2005	52	10 years	7	+ 2/24	MRM + CT	ER − PR−	PRESENT	AWD 25 m
This case	2010	19	9	2	+ 5/19	SM + ALND	ER + PR−	NE	AWD

ND: not defined, LE: local excision, MRM: modified radical mastectomy, CT: chemotherapy, RT radiotherapy, NE: not examined, NED: not evidence of disease, AWD: alive with disease, ER: estrogen receptor, PR: progesterone receptor, SM: simple mastectomy, ALNS: axillary lymph node sampling, ALND: axillary lymph node dissection, WLE: wide local excision, DOD: died of disease.