Research Article

Lymphangiogenesis and Axillary Lymph Node Metastases Correlated with VEGF-C Expression in Two Immunocompetent Mouse Mammary Carcinoma Models

Figure 6

TEM micrographs of lymphatic vessels in BJMC3879 tumors at 10 weeks postinoculation (a) and 4 weeks postinoculation (b). The boxed areas in (b) are observed with high-power view (c and d). (a) A leukocyte ( āˆ— ) is seen between endothelial cells (arrows), whereas tumor cells (arrowheads) are observed in the lumen. (b) Lymphatic capillary (arrow) and blood capillaries (arrowheads) are detected in the connective tissue surrounding tumors. Casein-like droplet (arrow) is located in the opening junction (c), and characteristic over-lapping junction (arrow) is showed (d).
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(c)
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(d)