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International Journal of Breast Cancer
Volume 2012 (2012), Article ID 671684, 1 page
Triple-Negative Breast Cancer
1Health Sciences Center, Louisiana State University, Shreveport, LA 71130, USA
2Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
3Department of Surgery, University of Texas Health Science Centre, San Antonis, TX 78229, USA
Received 8 February 2012; Accepted 8 February 2012
Copyright © 2012 Quyen D. Chu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Ever since the seminal work that was published by Perou et al., triple-negative breast cancer (TNBC) has become a common lexicon among clinicians who care for patients with breast cancer. Beside portending a poor outcome, TNBC is unique in that, unlike the hormone-positive and Her-2-positive cancer cells, it lacks target specific therapy. This is likely the result of our lack of having a clear understanding of its biology.
In this special issue, we were highly selective of only papers that we thought might further advance our understanding of the disease. Thus, the papers vary widely from the role of race/ethnicity to the metabolic/molecular influence that can potentially impact the biology of the disease.
We hope that this special issue will serve as a focal point to continue our ongoing discussion about this challenging entity.
Quyen D. Chu