Identifying Patients Who May Be Candidates for a Clinical Trial of Salvage Accelerated Partial Breast Irradiation after Previous Whole Breast Irradiation

Table 3

Comparison of tumor characteristics between initial and recurrent tumors.

	Initial	Recurrence
Detection method
Physical examination	32 (20%)	35 (22%)
Mammogram	63 (40%)	87 (55%)
PE + Mammogram	62 (35%)	29 (19%)
T stage	(pathologic)	(clinical)
Tis	20 (13%)	—
1	103 (65%)	90 (57%)
2	34 (22%)	14 (9%)
3/4	—	13 (9%)
N stage
0	136 (87%)	—
1	21 (8%)	—
2	8 (5%)	—
Tumor size
Median	1.0 cm	1.0 cm
Range	0.2–4.5 cm	0.2–5.5 cm
Histology
DCIS	20 (13%)	34 (22%)
Invasive ductal	121 (77%)	89 (57%)
Invasive lobular	9 (6%)	10 (6%)
Grade
1	9 (6%)	—
2	31 (20%)	—
3	51 (33%)	—
EIC
Positive	18 (12%)	—
Negative	73 (47%)	—
Receptor status
ER or PR +	88 (56%)	41 (26%)
ER and PR −	25 (16%)	20 (13%)
Margins
Negative	106 (67.5%)	—
Close	14 (9%)	—
Positive	6 (3.8%)	—