Clinical Study

Microcalcifications Detected as an Abnormality on Screening Mammography: Outcomes and Followup over a Five-Year Period

Table 1

Age distribution and final diagnostic outcome* of clients with calcifications assigned a breast imaging classification 3, 4, or 5 on screening mammogram.

(%)Total (%)

Age (years)
 <5018 (7.7)235 (100.0)
 50–59123 (52.3)
 60–6985 (36.2)
 ≥709 (3.8)
Final outcome
 Benign
  Benign191 (81.3)191 (81.3)
 Atypical
  ADH3 (1.3)6 (2.6)
  ALH3 (1.3)
 DCIS
  Low nuclear grade4 (1.7)20 (8.5)
  Intermediate nuclear grade6 (2.6)
  High nuclear grade10 (4.3)
 Invasive carcinoma
  Grade 1 7 (3.0)18 (7.7)
  Grade 2 5 (2.1)
  Grade 3 6 (2.6)

Outcome determined at assessment which may include results of FNA, UCNB, VALCS, or open surgical biopsy or surgical treatment pathology whichever is the latter.
89 cases (46.6% of the benign outcomes) did not undergo FNA, UCNB, VALCS, or open surgical biopsy.
Five of the 18 women with invasive carcinoma had nodal metastases (three with invasive carcinoma grade 3 had one metastatic node; one with invasive carcinoma grade 3 had 12 metastatic nodes; one with invasive carcinoma grade 1 had one metastatic node).
includes one case upgraded from DCIS to invasive carcinoma as a result of surgery.