Vascular Endothelial Growth Factor Receptor-1 Expression in Breast Cancer and Its Correlation to Vascular Endothelial Growth Factor A

Table 1

The final score VEGF expression in breast cancer patients and in patients with benign breast disease.

	LNT+; (𝑁T = 30, 𝑁OT = 30); 𝑁, ratio	LNT−; (𝑁T = 21, 𝑁OT = 18); 𝑁, ratio		BBD; (𝑁BBD = 30); 𝑁, ratio
VEGF expression score
T
0	2 (6.67)	2 (9.52)	0	28 (93.33)
+1	18 (60.00)	12 (51.14)
+2	9 (30.00)	7 (33.33)	+1	2 (6.67)
+3	1 (3.33)	0 (0.00)
ST
0	10 (33.33)	3 (16.67)	+2	0 (0.00)
+1	18 (60.00)	15 (83.33)
+2	2 (6.67)	0 (0.00)	+3	0 (0.00)
+3	0 (0.00)	0 (0.00)
Differences in VEGF expression between T and ST (Wilcoxon test), T and BT, and T and BT (Mann-Whitney test)	T/ST; 𝑧=−3.77𝑃=0.0001	T/ST; 𝑧=−2.45  𝑃=0.014	TLN+/BT; 𝑃=0.0001	TLN-/BT; 𝑃=0.0001
	TLN+/TLN-		STLN+/BT; 𝑃=0.0001	STLN−/BT; 𝑃=0.0001
	𝑃=0.002

LNT+: patients with positive lymph nodes, LNT−: patients with negative lymph nodes, BBD: benign breast disease patients, T: tumour, ST: surrounding tissue, and BT: breast tissue of patients with benign breast disease.