Review Article
Phenotypic and Molecular Characterization of MCF10DCIS and SUM Breast Cancer Cell Lines
Table 6
Protein expression of cytokeratins and CD49f/EPCAM in SUM cells.
| | Cell lines | CK5 (KRT5) | CK14 (KRT14) | CK8-18 | CK19 (KRT19) | CD49f (ITGA6) | CD146 (MCAM) | EpCAM (TACSTD1) | | IHC | IHC | IHC | IHC | IHC | FACS (s/n)a | FACS (s/n)a |
| | Normal like | | | | | | | |
| | SUM1315MO2 | + | − |
nd |
nd | + | 20–200 | <5 | | SUM159PT | − | − | − | − | +++ | 20–200 | <5 | | SUM102PT |
nd | − |
nd |
nd |
nd | 520 | <5 |
| | Basal | | | | | | | |
| | SUM149PT | ++++ | − | ++++ | ++ | + | 20–200 | 20–200 | | SUM229PE | +++ | − | ++++ | ++ | + | 20–200 | 20–200 |
| | Luminal | | | | | | | |
| | SUM44PE | − | − |
nd | +++ | ++++ |
nd |
nd | | SUM185PE | − | − | ++++ | +++ | ++++ |
nd |
nd |
|
|
Source: [35, 77].
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