Breast Cancer with Neoductgenesis: Histopathological Criteria and Its Correlation with Mammographic and Tumour Features

Table 2

Baseline characteristics in 74 women with DCIS with or without an invasive component.

Characteristics	All cases; ()	Pure DCIS; ()	DCIS with an invasive component ()
	Number (%)	Number (%)	Number (%)
Age at diagnosis
≤55 years	29 (39.2)	14 (43.8)	15 (35.7)
>55 years	45 (60.8)	18 (56.2)	27 (64.3)
Mammographic casting type or crushed stone-like calcifications
Yes	48 (64.9)	23 (71.9)	25 (59.5)
No	26 (31.1)	9 (28.1)	17 (40.5)
Cytonuclear grade
2	26 (35.1)	7 (21.9)	19 (45.2)
3	48 (64.9)	25 (78.1)	23 (54.8)
ER
Positive	53 (71.6)	22 (68.8)	31 (73.8)
Negative	18 (24.3)	7 (21.9)	11 (26.2)
Missing	3 (4.1)	3 (9.3)	0
PR
Positive	42 (56.7)	18 (56.2)	23 (57.1)
Negative	29 (39.2)	11 (34.4)	16 (47.9)
Missing	3 (4.1)	3 (9.4)	0
HER2
Positive	29 (39.2)	13 (40.6)	16 (38.1)
Negative	40 (54.1)	15 (46.9)	25 (59.5)
Missing	5 (6.8)	4 (12.5)	1 (2.4)
Ki67
High	22 (29.7)	7 (21.9)	15 (35.7)
Low	47 (63.5)	21 (65.6)	26 (61.9)
Missing	5 (6.8)	4 (12.5)	1 (2.4)
Tenascin-C
Positive	40 (54.0)	16 (50.0)	24 (57.1)
Negative	11 (14.9)	5 (15.6)	6 (14.3)
Missing	23 (31.1)	11 (34.4)	12 (28.6)
Concentration of duct-like structures*
No	17 (23.0)	4 (12.5)	13 (31.0)
Focal	33 (44.6)	15 (46.9)	18 (42.8)
General	24 (32.4)	13 (40.6)	11 (26.2)
Lymphocytic infiltration*
No	26 (35.1)	13 (40.6)	13 (31.0)
Mild	29 (39.2)	12 (37.5)	17 (40.5)
Intense	19 (25.7)	7 (21.9)	12 (28.5)
Fibrosis-like thickening of the periductal stroma*
No	8 (10.8)	3 (9.4)	5 (11.9)
Mild	52 (70.3)	24 (75.0)	28 (66.7)
Intense	14 (18.9)	5 (15.6)	9 (21.4)
Neoductgenesis**
Yes, 17–24	23 (31.1)	9 (28.1)	14 (33.3)
No, 0–16	51 (68.9)	23 (71.9)	28 (66.7)

*The value is based on the average score among the four pathologists.
**The value is based on the combined scores among the four pathologists.