Locoregional and Distant Recurrence Patterns in Young versus Elderly Women Treated for Breast Cancer
Table 2
Univariate analysis of risk factors for locoregional free survival in younger women.
Characteristic
(%)*
Hazard ratio (95% CI)
Hazard ratio value
Log-rank value
Receptor status
ER/PR+#
71 (62.28)
0.35 (0.15–0.85)
0.021
0.033
Her2+
11 (9.65)
0.34 (0.06–1.99)
0.231
Triple negative
32 (28.07)
—
Grade
1
14 (12.61)
1.11 (0.36–3.42)
0.854
0.949
2
35 (31.53)
0.90 (0.34–2.40)
0.832
3
62 (55.86)
—
Surgery type
Lumpectomy
69 (55.2)
1.20 (0.52–2.73)
0.672
0.634
Mastectomy
56 (44.8)
—
Adjuvant chemotherapy
No
87 (69.6)
0.87 (0.38–1.99)
0.736
0.781
Yes
38 (30.4)
—
Neoadjuvant chemotherapy
No
41 (32.8)
1.83 (0.82–4.07)
0.137
0.134
Yes
84 (67.2)
—
Detected on mammography
No
103 (88.03)
0.40 (0.15–1.05)
0.062
0.075
Yes
14 (11.97)
—
Stage at diagnosis
0/I
25 (21.01)
2.02 (0.85–4.79)
0.111
0.120
II/III
94 (78.99)
—
Nodal status
Positive
41 (32.8)
0.78 (0.33–1.85)
0.572
0.512
Negative
84 (67.2)
—
Postmastectomy radiation
No
16 (28.57)
1.18 (0.30–4.66)
0.816
0.901
Yes
40 (71.43)
—
Postlumpectomy radiation
No
5 (7.25)
6.34 (1.46–27.55)
0.014
0.017
Yes
64 (92.75)
—
Final margin status
Positive
(1.63)
1.92 (0.10–36.83)
0.665
0.774
Less than 2 mm
14 (11.38)
1.55 (0.47–5.09)
0.474
Greater than 2 mm
107 (86.99)
—
*Total patients for each characteristic may vary due to incomplete medical records for some patients. #ER/PR+: estrogen receptor/progesterone receptor positive.
