Clinical Study
Surgical Site Infections in Breast Surgery: The Use of Preoperative Antibiotics for Elective, Nonreconstructive Procedures
Table 3
Cross-tab analysis of clinical characteristics and antibiotic use in relation to SSI rate.
| | No infection | Surgical site infection | value† | | | |
| No prior operation within 30 days | | | <0.0001 | No antibiotics | 366 (47%) | 13 (18%) | | Single dose of antibiotics | 386 (49%) | 51 (72%) | | Prior operation within 30 days | | | 0.6766 | No antibiotics | 19 (2%) | 3 (4%) | | Single dose of antibiotics | 13 (2%) | 4 (6%) | |
| Male patients | | | NA | No antibiotics | 11 (1%) | 0 (0%) | | Single dose of antibiotics | 9 (1%) | 0 (0%) | | Female patients | | | <0.0001 | No antibiotics | 374 (48%) | 16 (23%) | | Single dose of antibiotics | 390 (50%) | 55 (77%) | |
| Small surface area | | | 0.0170 | No antibiotics | 317 (40%) | 7 (10%) | | Single dose of antibiotics | 110 (14%) | 9 (13%) | | Large surface area | | | 0.7136 | No antibiotics | 68 (9%) | 9 (13%) | | Single dose of antibiotics | 289 (37%) | 46 (65%) | |
| No wire localization | | | 0.1791 | No antibiotics | 130 (17%) | 13 (18%) | | Single dose of antibiotics | 314 (40%) | 50 (70%) | | Wire localization placed | | | 0.0299 | No antibiotics | 255 (33%) | 3 (4%) | | Single dose of antibiotics | 85 (11%) | 5 (7%) | |
| Nondiabetic patients | | | 0.0002 | No antibiotics | 338 (43%) | 14 (20%) | | Single dose of antibiotics | 363 (46%) | 46 (65%) | | Diabetic patients | | | 0.0233 | No antibiotics | 47 (6%) | 2 (3%) | | Single dose of antibiotics | 36 (5%) | 9 (13%) | |
| BMI ≤ 25 | | | 0.1904 | No antibiotics | 108 (14%) | 3 (4%) | | Single dose of antibiotics | 83 (11%) | 6 (9%) | | BMI > 25 | | | <0.0001 | No antibiotics | 277 (35%) | 13 (18%) | | Single dose of antibiotics | 316 (40%) | 49 (69%) | |
| Surgery age ≤ 50 | | | 0.0009 | No antibiotics | 125 (16%) | 3 (4%) | | Single dose of antibiotics | 208 (27%) | 30 (42%) | | Surgery age > 50 | | | 0.0062 | No antibiotics | 260 (33%) | 13 (18%) | | Single dose of antibiotics | 191 (24%) | 25 (35%) | |
| Any breast procedure not including mastopexy or reduction mammaplasty | | | 0.0089 | No antibiotics | 379 (48%) | 16 (23%) | | Single dose of antibiotics | 177 (23%) | 19 (27%) | | Mastopexy or reduction mammaplasty | | | 1.0000 | No antibiotics | 6 (1%) | 0 (0%) | | Single dose of antibiotics | 222 (28%) | 36 (51%) | |
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value was derived from Fisher’s Exact test. Not applicable.
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