Clinical Study

Surgical Site Infections in Breast Surgery: The Use of Preoperative Antibiotics for Elective, Nonreconstructive Procedures

Table 3

Cross-tab analysis of clinical characteristics and antibiotic use in relation to SSI rate.

No infectionSurgical site infection value

No prior operation within 30 days<0.0001
 No antibiotics366 (47%)13 (18%)
 Single dose of antibiotics386 (49%)51 (72%)
Prior operation within 30 days0.6766
 No antibiotics19 (2%)3 (4%)
 Single dose of antibiotics13 (2%)4 (6%)

Male patientsNA
 No antibiotics11 (1%)0 (0%)
 Single dose of antibiotics9 (1%)0 (0%)
Female patients<0.0001
 No antibiotics374 (48%)16 (23%)
 Single dose of antibiotics390 (50%)55 (77%)

Small surface area0.0170
 No antibiotics317 (40%)7 (10%)
 Single dose of antibiotics110 (14%)9 (13%)
Large surface area0.7136
 No antibiotics68 (9%)9 (13%)
 Single dose of antibiotics289 (37%)46 (65%)

No wire localization0.1791
 No antibiotics130 (17%)13 (18%)
 Single dose of antibiotics314 (40%)50 (70%)
Wire localization placed0.0299
 No antibiotics255 (33%)3 (4%)
 Single dose of antibiotics85 (11%)5 (7%)

Nondiabetic patients0.0002
 No antibiotics338 (43%)14 (20%)
 Single dose of antibiotics363 (46%)46 (65%)
Diabetic patients0.0233
 No antibiotics47 (6%)2 (3%)
 Single dose of antibiotics36 (5%)9 (13%)

BMI ≤ 250.1904
 No antibiotics108 (14%)3 (4%)
 Single dose of antibiotics83 (11%)6 (9%)
BMI > 25<0.0001
 No antibiotics277 (35%)13 (18%)
 Single dose of antibiotics316 (40%)49 (69%)

Surgery age ≤ 500.0009
 No antibiotics125 (16%)3 (4%)
 Single dose of antibiotics208 (27%)30 (42%)
Surgery age > 500.0062
 No antibiotics260 (33%)13 (18%)
 Single dose of antibiotics191 (24%)25 (35%)

Any breast procedure not including mastopexy or reduction mammaplasty0.0089
 No antibiotics379 (48%)16 (23%)
 Single dose of antibiotics177 (23%)19 (27%)
Mastopexy or reduction mammaplasty1.0000
 No antibiotics6 (1%)0 (0%)
 Single dose of antibiotics222 (28%)36 (51%)

value was derived from Fisher’s Exact test.
Not applicable.