Coverage of Axillary Lymph Nodes with Tangential Breast Irradiation in Korea: A Multi-Institutional Comparison Study
Table 2
Dose-volume parameters comparison between the three institutions.
Targets
Dose-volume parameters
Mean (range)
p
Institution A
Institution B
Institution C
DHS
Mean length (cm)
3.6 (1.0–6.0)
2.9 (0.5–4.5)
0.7 (−1.0–2.0)
0.001
Level I
Mean dose (Gy)
23.8 (9.9–37.8)
27.0 (16.1–42.1)
44.8 (39.8–47.9)
<0.001
(Gy)
2.6 (0.4–10.1)
3.3 (1.0–12.2)
29.6 (5.7–43.0)
0.001
(Gy)
19.9 (1.1–44.5)
25.4 (3.6–48.8)
47.4 (45.4–48.8)
0.001
(%)
13.0 (0.2–23.5)
26.4 (2.6–63.5)
47.5 (1.6–74.1)
0.002
(%)
47.0 (14.9–80.0)
52.0 (26.5–89.7)
94.6 (81.1–100)
<0.001
Level II
Mean dose (Gy)
12.9 (3.4–20.4)
18.6 (13.7–30.3)
35.4 (27.2–47.7)
<0.001
(Gy)
1.0 (0.3–2.0)
1.1 (0.6–1.8)
7.0 (1.5–40.0)
0.324
(Gy)
4.2 (0.7–16.3)
9.7 (1.8–43.3)
44.0 (36.7–48.6)
<0.001
(%)
1.6 (0.0–7.3)
11.4 (0.0–28.7)
21.5 (0.0–70.1)
0.014
(%)
25.0 (5.1–42.1)
36.4 (24.7–61.7)
74.9 (55.8–100)
<0.001
Lung
Mean dose (Gy)
6.3 (3.9–9.7)
6.7 (5.0–8.5)
8.3 (6.4–10.0)
0.021
(%)
17.4 (10.9–28.2)
21.9 (16.3–26.9)
28.7 (23.6–32.3)
<0.001
(%)
13.5 (8.3–20.9)
14.9 (10.5–19.5)
19.1 (14.2–23.3)
0.006
(%)
11.0 (6.3–16.8)
11.4 (7.6–15.5)
14.4 (9.8–18.9)
0.061
Heart†
Mean dose (Gy)
2.2 (0.9–3.3)
2.3 (1.2–3.5)
3.7 (1.1–7.8)
0.286
(%)
0.9 (0.0–2.0)
1.8 (0.3–3.7)
1.8 (0.0–3.3)
0.449
DHS: distance from the humeral head to the superior border of the tangential field; : dose delivered to 95% of the target; : dose delivered to 50% of the target; : percent volume of the target receiving 95% of the prescribed dose; : percent volume of the target receiving 50% of the prescribed dose; : percent volume of the lung receiving 5 Gy; : percent volume of the lung receiving 10 Gy; : percent volume of the lung receiving 20 Gy; : percent volume of the heart receiving 30 Gy. Minus value means that the superior border of the tangential field was set above the humeral head. †Percent volume of the heart receiving 30 Gy () and mean dose received by heart were calculated for 5 patients with left-sided breast cancer.
