Research Article

Promoter Methylation Status of Breast Cancer Susceptibility Gene 1 and 17 Beta Hydroxysteroid Dehydrogenase Type 1 Gene in Sporadic Breast Cancer Patients

Table 8

Relation between combined BRCA1 and 17βHSD-1 promoter methylation and the type of breast tissues of 40 sporadic breast cancer patients.

Combined BRCA1 and 17βHSD-1 promoter methylation
⁢⁢Overall ()⁢⁢Methylated⁢⁢Unmethylated valueOR (95% CI)
Freq.%Freq.(%)Freq.(%)

Type of tissue
 Cancer tissues40100.0%18(45.0)22(55.0)0.3611.5 (0.6–3.7)
 Normal tissues 40100.0%14(35.0)26(65.0)
Total80100.0%32(40.0)48(60.0)

Chi-square test is statistically significant at 95% confidence level.