Ductal Breast Carcinoma In Situ: Mammographic Features and Its Relation to Prognosis and Tumour Biology in a Population Based Cohort
Table 2
The correlation between histopathological features of neoductgenesis and patient and tumour characteristics in 458 cases with DCIS. Eight cases could not be classified.
Neoductgenesis
value
Yes () Number (%)
No () Number (%)
Age at diagnosis ()
≤55 years
25 (43.2)
174 (42.9)
0.08
>55 years
19 (56.8)
232 (57.1)
Mammographic casting type calcifications ()
Yes
7 (16.3)
82 (21.5)
0.42
No
36 (83.7)
299 (78.5)
Nuclear grade ()
1
2 (4.5)
37 (9.1)
<0.001
2
5 (11.4)
167 (41.1)
3
37 (84.1)
202 (49.8)
ER ()
≥10%
15 (36.6)
273 (73.8)
<0.001
<10%
26 (63.4)
97 (26.2)
PR ()
≥10%
7 (18.4)
190 (52.1)
<0.001
<10%
31 (81.6)
175 (47.9)
HER2 ()
Positive
30 (69.8)
100 (27.8)
<0.001
Normal
13 (30.2)
260 (72.2)
Ki67 ()
High
27 (69.2)
104 (31.7)
<0.001
Low
12 (30.8)
224 (68.3)
Tenascin-C ()
High
20 (55.6)
92 (34.3)
0.01
Low
16 (44.4)
176 (65.7)
Neoductgenesis was defined as a score of 4 to 6 points, combining the scores for concentration of ducts (0–2), lymphocytic infiltration (0–2), and periductal fibrosis (0–2).
