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International Journal of Breast Cancer
Volume 2017, Article ID 9574874, 7 pages
https://doi.org/10.1155/2017/9574874
Research Article

Obesity and Prognostic Variables in Colombian Breast Cancer Patients: A Cross-Sectional Study

1Clinical Oncology Group, Fundación Colombiana de Cancerología-Clínica Vida, Medellín, Colombia
2Breast Surgeon Fellowship Program, School of Medicine, CES University, Medellín, Colombia
3Department of Clinical Epidemiology, School of Medicine, CES University, Medellín, Colombia

Correspondence should be addressed to Javier Cuello-López; moc.liamtoh@lcamaj

Received 24 January 2017; Accepted 12 April 2017; Published 18 May 2017

Academic Editor: Owen A. Ung

Copyright © 2017 Javier Cuello-López et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Introduction. Obesity is an established risk factor for cancer and cancer-related deaths, including that of the breast. While the prevalence of female obesity has accelerated over the past decade in many developing countries, such as Colombia, the prevalence of overweight and obesity specifically in breast cancer populations has not been fully described. Methods. A cross-sectional study including 849 women diagnosed with breast cancer between 2009 and 2014. Based on body mass index, prevalence of overweight (BMI ≥ 25 < 30) and obesity (BMI ≥ 30) and associations of BMI with clinical and tumor histopathological features were analyzed. Results. Colombian breast cancer patients had a prevalence of overweight of 34.28% and obesity of 28.15%. Mean BMI was comparable between premenopausal and postmenopausal women (27.2 versus 27.7, resp.). Among premenopausal women, higher BMI was significantly positively associated with hormone receptor negative tumors, as well as with greater lymphovascular invasion. Conclusions. Colombian breast cancer patients exhibit a significant prevalence of overweight and obesity. Associations of high BMI and poor prognosis variables in the premenopausal population suggest risk of aggressive disease in this population. Future studies to further validate our observations are warranted in order to implement multidisciplinary clinical guidelines.