Research Article

Germline Mutations in BRCA1 and BRCA2 in Breast Cancer Patients with High Genetic Risk in Turkish Population

Table 1

The characteristics of the patients.

Characteristicsn

Menopause StatusPremenopause6868
Postmenopause3131

Family HistoryFirst-degree relative2121.2
Second-degree relative88.08

Tumor LocalizationRight4747
Left4545
Bilateral77

Tumor HistologyInvasive ductal carcinoma8686
Invasive lobular carcinoma1010
Others33

Receptor StatusER positive6060
ER negative3939
PR positive5353
PR negative4646
HER2 positive1010
HER2 negative8989
Triple-negative3333

High Risk FactorsFirst-degree relative2121
Bilateral carcinoma77
Breast + Ovarian carcinoma77
Triple-negative3333
Below 40 years old4141