Research Article
Germline Mutations in BRCA1 and BRCA2 in Breast Cancer Patients with High Genetic Risk in Turkish Population
Table 1
The characteristics of the patients.
| Characteristics | n | |
| Menopause Status | Premenopause | 68 | 68 | Postmenopause | 31 | 31 |
| Family History | First-degree relative | 21 | 21.2 | Second-degree relative | 8 | 8.08 |
| Tumor Localization | Right | 47 | 47 | Left | 45 | 45 | Bilateral | 7 | 7 |
| Tumor Histology | Invasive ductal carcinoma | 86 | 86 | Invasive lobular carcinoma | 10 | 10 | Others | 3 | 3 |
| Receptor Status | ER positive | 60 | 60 | ER negative | 39 | 39 | PR positive | 53 | 53 | PR negative | 46 | 46 | HER2 positive | 10 | 10 | HER2 negative | 89 | 89 | Triple-negative | 33 | 33 |
| High Risk Factors | First-degree relative | 21 | 21 | Bilateral carcinoma | 7 | 7 | Breast + Ovarian carcinoma | 7 | 7 | Triple-negative | 33 | 33 | Below 40 years old | 41 | 41 |
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