Association between Lymph Node Status and Expression Levels of Androgen Receptor, miR-185, miR-205, and miR-21 in Breast Cancer Subtypes

Table 2

The association between the levels of miR-205, miR-185, miR-21, and AR mRNA in tissue samples from patients and subtype of breast cancer.

Subtype	Number of patients	Relative level of miRNA or mRNA and value
		miR-205	value	miR-185	value	miR-21	value	AR	value
Luminal A	24	0.25 (0.09-2.14)	0.070	0.55 (0.12-2.03)	0.136	5.14 (0.79-35.15)	<0.001	0.85 (0.35-2.35)	0.295
Luminal B (HER2-negative)	20	0.21 (0.06-2.91)	0.041	0.25 (0.06-1.54)	0.005	3.53 (0.87-37.83)	<0.001	0.91 (0.44-2.35)	0.438
Luminal B (HER2-positive)	20	0.25 (0.03-1.56)	0.003	0.28 (0.08-3.16)	0.035	13.98 (0.39-64.68)	0.002	0.88 (0.29-2.40)	0.381
HER2-positive	13	0.52 (0.11-1.39)	0.115	0.48 (0.11-1.60)	0.115	6.68 (0.72-20.50)	0.018	0.33 (0.04-0.74)	0.001
Triple-negative	12	0.19 (0.03-0.94)	0.001	0.41 (0.09-1.42)	0.104	5.02 (0.81-21.54)	0.027	0.12 (0.01-0.31)	<0.001

Median and range of relative change of microRNA or mRNA levels in the breast tumor versus paired normal (adjoining) tissue.