In Vitro Growth Inhibition, Caspase-Dependent Apoptosis, and S and G2/M Phase Arrest in Breast Cancer Cells Induced by Fluorine-Incorporated Gold I Compound, Ph3PAu[SC(OMe)=NC6H4F-3]

Figure 4

Breast cancer cells under the inverted microscopic view and on the screen view of Luna-FL. Microscopic view for MDA-MB-231 (control: (a), treated: (b)), MCF-7 (control: (c), treated: (d)). Luna-FL on-screen view of AO/PI-stained MDA-MB-231 (control: (e), treated: (f)), MCF-7 (control: (g), treated: (h)). LC: live cells; DC: dead cells; LB: membrane blebbing; CS: cell shrinkage. Cells were treated with the IC₅₀ dose (8.5 μM for MDA-MB-231 and 6.5 μM for MCF-7) of compound 3F1 for the test samples or 0.1% DMSO for the control samples for 24 h. AO/PI-stained cells were viewed and counted on the Luna-FL (Logos Biosystems, Korea).

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