International Journal of Biomedical Imaging
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Acceptance rate19%
Submission to final decision96 days
Acceptance to publication21 days
CiteScore8.200
Journal Citation Indicator0.790
Impact Factor-

Towards an Accurate MRI Acute Ischemic Stroke Lesion Segmentation Based on Bioheat Equation and U-Net Model

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International Journal of Biomedical Imaging aims to promote research and development of biomedical imaging by publishing high-quality research articles and reviews in this rapidly growing interdisciplinary field.

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International Journal of Biomedical Imaging maintains an Editorial Board of practicing researchers from around the world, to ensure manuscripts are handled by editors who are experts in the field of study.

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Research Article

Left Ventricle Segmentation in Cardiac MR Images via an Improved ResUnet

Cardiovascular diseases are reported as the leading cause of death around the world. Automatic segmentation of the left ventricle (LV) from magnetic resonance (MR) images is essential for an early diagnosis. An enhanced ResUnet is proposed in this paper to improve the performance of extracting LV endocardium and epicardium from MR images, improving the accuracy of the model by introducing a medium skip connection for the contracting path and a short skip connection for the residual unit. Also, a depth-wise separable convolution replaces the typical convolution operation to improve training efficiency. In the MICCAI 2009 LV segmentation challenge test dataset, the percentages of “good” contours, dice metric, and average perpendicular distance of endocardium (epicardium) are , respectively. Experimental results demonstrate that the proposed model obtains promising performance and outperforms state-of-the-art methods. By incorporating these various skip connections, the segmentation accuracy of the model is significantly improved, while the depth-wise separable convolution also improves the model efficiency.

Research Article

Myocardium Assessment by Relaxation along Fictitious Field, Extracellular Volume, Feature Tracking, and Myocardial Strain in Hypertensive Patients with Left Ventricular Hypertrophy

Background. Previous research has shown impaired global longitudinal strain (GLS) and slightly elevated extracellular volume fraction (ECV) in hypertensive patients with left ventricular hypertrophy (HTN LVH). Up to now, only little attention has been paid to interactions between macromolecules and free water in hypertrophied myocardium. Purpose. To evaluate the feasibility of relaxation along a fictitious field with rank 2 (RAFF2) in HTN LVH patients. Study Type. Single institutional case control. Subjects. 9 HTN LVH (age, years) and 11 control subjects (age, years). Field Strength/Sequence. Relaxation time mapping (, , and with 11.8 μT maximum radio frequency field amplitude) was performed at 1.5 T using a Siemens Aera (Erlangen, Germany) scanner equipped with an 18-channel body array coil. Assessment. ECV was calculated using pre- and postcontrast , and global strains parameters were assessed by Segment CMR (Medviso AB Co, Sweden). The parametric maps of and were computed using a monoexponential model, while the Bloch-McConnell equations were solved numerically to model effect of the chemical exchange during radio frequency pulses. Statistical Tests. Parametric maps were averaged over myocardium for each subject to be used in statistical analysis. Kolmogorov-Smirnov was used as the normality test followed by Student’s t-test and Pearson’s correlation to determine the difference between the HTN LVH patients and controls along with Hedges’ effect size and the association between variables, respectively. Results. decreased statistically , and global longitudinal strain was impaired (GLS, ) in HTN LVH patients compared to the controls, respectively. Also, significant negative correlation was found between and GLS . Data Conclusion. Our results suggest that decrease in HTN LVH patients may be explained by gradual collagen accumulation which can be reflected in GLS changes. Most likely, it increases the water proton interactions and consequently decreases before myocardial scarring.

Research Article

Relative Perfusion Differences between Parathyroid Adenomas and the Thyroid on Multiphase 4DCT

A multiphase 4DCT technique can be useful for the detection of parathyroid adenomas. Up to 16 different phases can be obtained without significant increase of exposure dose using wide beam axial scanning. This technique also allows for the calculation of perfusion parameters in suspected lesions. We present data on 19 patients with histologically proven parathyroid adenomas. We find a strong correlation between 2 perfusion parameters when comparing parathyroid adenomas and thyroid tissue: parathyroid adenomas show a 55% increase in blood flow (BF) () and a 50% increase in blood volume (BV) () as compared to normal thyroid tissue. The analysis of the ROC curve for the different perfusion parameters demonstrates a significantly high area under the curve for BF and BV, confirming these two perfusion parameters to be a possible discriminating tool to discern between parathyroid adenomas and thyroid tissue. These findings can help to discern parathyroid from thyroid tissue and may aid in the detection of parathyroid adenomas.

Research Article

MRI Reconstruction with Separate Magnitude and Phase Priors Based on Dual-Tree Complex Wavelet Transform

The methods of compressed sensing magnetic resonance imaging (CS-MRI) can be divided into two categories roughly based on the number of target variables. One group devotes to estimating the complex-valued MRI image. And the other calculates the magnitude and phase parts of the complex-valued MRI image, respectively, by enforcing separate penalties on them. We propose a new CS-based method based on dual-tree complex wavelet (DT CWT) sparsity, which is under the frame of the second class of CS-MRI. Owing to the separate regularization frame, this method reduces the impact of the phase jumps (that means the jumps or discontinuities of phase values) on magnitude reconstruction. Moreover, by virtue of the excellent features of DT CWT, such as nonoscillating envelope of coefficients and multidirectional selectivity, the proposed method is capable of capturing more details in the magnitude and phase images. The experimental results show that the proposed method recovers the image contour and edges information well and can eliminate the artifacts in magnitude results caused by phase jumps.

Review Article

A Concise Review on the Utilization of Abbreviated Protocol Breast MRI over Full Diagnostic Protocol in Breast Cancer Detection

Breast MRI possesses high sensitivity for detecting breast cancer among the current clinical modalities and is an indispensable imaging practice. Breast MRI comprises diffusion-weighted imaging, ultrafast, and T2 weighted and T1 weighted CE (contrast-enhanced) imaging that may be utilized for improving the characterization of the lesions. This multimodal evaluation of breast lesions enables outstanding discrimination between the malignant and benign and malignant lesions. The expanding indications of breast MRI confirm the far superiority of MRI in preoperative staging, especially in the estimation of tumour size and identifying tumour foci in the contralateral and ipsilateral breast. Recent studies depicted that experts can meritoriously utilize this tool for improving breast cancer surgery despite their existence of no significant long term outcomes. For managing the, directly and indirectly, associated screening cost, abbreviated protocols are found to be more beneficial. Further, in some of the patients who were treated with neoadjuvant chemotherapy, breast MRI is utilized for documenting response. It is therefore essential to realise that oncological screening must be easily available, cost-effective, and time-consuming. Earlier detection of this short sequence protocol leads to prior and early breast cancer disease in high risky female populations like women with dense breasts, prehistoric evidence, etc. This proper utilization of AP reduces unnecessary mastectomies. Hence, this review focused on the explorative information for strongly suggesting the benefits of AP breast MRI compared to full diagnostic protocol MRI.

Research Article

Content-Based Image Retrieval Using Colour, Gray, Advanced Texture, Shape Features, and Random Forest Classifier with Optimized Particle Swarm Optimization

In this paper, a new approach for Content-Based Image Retrieval (CBIR) has been addressed by extracting colour, gray, advanced texture, and shape features for input query images. Contour-based shape feature extraction methods and image moment extraction techniques are used to extract the shape features and shape invariant features. The informative features are selected from extracted features and combined colour, gray, texture, and shape features by using PSO. The target image has been retrieved for the given query image by training the random forest classifier. The proposed colour, gray, advanced texture, shape feature, and random forest classifier with optimized PSO (CGATSFRFOPSO) provide efficient retrieval of images in a large-scale database. The main objective of this research work is to improve the efficiency and effectiveness of the CBIR system by extracting the features like colour, gray, texture, and shape from database images and query images. These extracted features are processed in various levels like removing redundancy by optimal feature selection and fusion by optimal weighted linear combination. The Particle Swarm Optimization algorithm is used for selecting the informative features from gray and colour and texture features. The matching accuracy and the speed of image retrieval are improved by an ensemble of machine learning algorithms for the similarity search.

International Journal of Biomedical Imaging
 Journal metrics
See full report
Acceptance rate19%
Submission to final decision96 days
Acceptance to publication21 days
CiteScore8.200
Journal Citation Indicator0.790
Impact Factor-
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