Review Article

Contribution of Exploratory Methods to the Investigation of Extended Large-Scale Brain Networks in Functional MRI: Methodologies, Results, and Challenges

Table 1

Literature summary of the different networks found in network investigation of fMRI data. Methods—HC: hierarchical clustering, SOM: self-organizing map algorithm, ICA: independent component analysis. Networks—M/SM: motor/sensorimotor, V: visual, A: auditory, DM: default mode, dAtt: dorsal attentional, vAtt: ventral attentional, EC: executive control. Networks found are denoted by “X.” (*) In addition to primary cortices (sensorimotor, visual, and auditory), the clusters shown by Cordes et al. [63] were essentially bilateral single regions (thalami, fusiform gyri, and frontal gyri) which were parts of different networks of reference. ( ) Except for the sensorimotor system, the networks identified by Peltier et al. [61] were not properly labeled; the spatial organizations of the maps shown seemed similar to the attentional networks. ( ) The results presented by Calhoun et al. [73] were partial, mentioning the extraction of other networks that they did not show neither comment; another study on similar datasets showed that the sensorimotor and the dorsal attentional networks might be detected too [74].

TaskReferenceMethodNetwork
M/SMVADMdAttvAttEC

At rest[61]HCXXXX(*)X(*)
[63]SOMX( )( )
[73]ICAXXXX
[75]ICAXXXXXX
[76]ICAXXXXXXX
[77]ICAXXXXX

Blocked visual[78]ICAX( )XXX( )
[79]ICAXXX

Blocked motor[80]LSNIXXX