Research Article

Multiscale Characterization of the PEPCK- Mouse through 3D Cryoimaging

Figure 6

Pericardial adipose tissue. The PEPCK- mouse has less pericardial adipose tissue (a) compared to the control animal (b) as shown in the yellow outlines on the coronal section images. From the 2D images the heart was reconstructed in 3D with the pericardial fat rendered in white for PEPCK- (c) and control mouse (d). The rendering for fat was done in lower transparency so that the heart can be seen through it. Pericardial fat is considered an ageing biomarker. Note in (c) that the coronary vessels are clearly seen on the 3D surface of the heart (Bar = 1 mm).
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(a)
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(b)
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(c)
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(d)