Statistical Evaluations of the Reproducibility and Reliability of 3-Tesla High Resolution Magnetization Transfer Brain Images: A Pilot Study on Healthy Subjects

Table 10

Sensitivity analysis of 6 different interobserver ICCs.

Region of Interest	ICC (1,1)	ICC (2,1)	ICC (3, 1)	ICC (1, 2)	ICC (2, 2)	ICC (3, 2)
Interobserver ICC at Time 1
Genu	0.870	0.879	0.866	0.931	0.935	0.928
Splenium	0.497	0.463	0.537	0.664	0.633	0.699
Left Hippocampus	0.653	0.605	0.693	0.790	0.754	0.819
Left Caudate	0.562	0.542	0.580	0.719	0.703	0.734
Left Putamen	0.871	0.874	0.869	0.931	0.933	0.930
Left Thalamus	−0.015	0.114	0.410	−0.030	0.205	0.581
Left Cerebral White Matter	0.382	0.385	0.378	0.553	0.556	0.549
Right Hippocampus	0.660	0.669	0.653	0.795	0.802	0.790
Right Caudate	0.178	0.180	0.209	0.302	0.306	0.346
Right Putamen	0.725	0.732	0.720	0.840	0.845	0.837
Right Thalamus	−0.092	0.079	0.264	−0.202	0.146	0.417
Right Cerebral White Matter	0.630	0.621	0.637	0.773	0.766	0.779
Interobserver ICC at Time 2
Genu	0.722	0.715	0.726	0.838	0.834	0.841
Splenium	0.758	0.757	0.758	0.862	0.862	0.863
Left Hippocampus	0.792	0.785	0.796	0.884	0.880	0.886
Left Caudate	0.905	0.909	0.902	0.950	0.952	0.949
Left Putamen	0.961	0.959	0.962	0.980	0.979	0.980
Left Thalamus	0.297	0.239	0.855	0.458	0.385	0.922
Left Cerebral White Matter	0.928	0.926	0.929	0.963	0.962	0.963
Right Hippocampus	0.640	0.620	0.656	0.781	0.765	0.793
Right Caudate	0.876	0.884	0.872	0.934	0.938	0.932
Right Putamen	0.884	0.887	0.882	0.938	0.940	0.937
Right Thalamus	0.419	0.347	0.572	0.591	0.516	0.728
Right Cerebral White Matter	0.889	0.876	0.896	0.941	0.934	0.945