Statistical Evaluations of the Reproducibility and Reliability of 3-Tesla High Resolution Magnetization Transfer Brain Images: A Pilot Study on Healthy Subjects

Table 4

Six different ICCs computed via a sensitivity analysis of the modeling choices.

Notation for the ICC Measure	Multivariate Modeling Assumptions
ICC(1,1)	Each subject is rated by multiple observers; the observers are assumed to be randomly assigned to the subjects; all subjects have the same number of observers.
ICC(2,1)	All subjects are rated by the same observers who are assumed to be a random subset of all possible observers.
ICC(3,1)	All subjects are rated by the same observers who are assumed to be the entire population of observers.
ICC(1,2)	Same assumptions as ICC(1,1) but reliability for the mean of 2 ratings.
ICC(2,2)	Same assumptions as ICC(2,1) but reliability for the mean of 2 ratings.
ICC(3,2)	Same assumptions as ICC(3,1) but reliability for the mean of 2 ratings. Assumes additionally there is no subject × observer interaction.