Hybrid ICA-Seed-Based Methods for fMRI Functional Connectivity Assessment: A Feasibility Study

Table 2

Experiment 2: mean percentages of thresholded task-related GLM maps that are covered by thresholded FC maps generated with each hybrid ICA-seed-based method. The right-most column gives percentages after adjusting the z-score used to threshold the FC maps up or down so that number of false positives equals number of false negatives.

Source of time course regressor(s)	Percent of Task-Related Map Covered (95% Confidence Interval)
	Before Threshold Adjustment
Single voxel	94 (92–97)	78 (72–83)
Average over 5 voxels	94 (92–97)	78 (73–83)
Average over 118 voxels	95 (93–98)	87 (84–90)
Regression against 1 spatial map	95 (93–98)	84 (81–87)
Regression against all spatial maps	96 (94–97)	83 (80–85)