Figure 10: Registration results of neonates mapped to 2-year olds. From left to right: (a) neonatal T1 image after affine registration, (b) reference T1 image at 2 years, followed by (c) neonatal T1 after deformable mutual information registration using B-splines, and (d) after combined probabilistic and geometric registration. From top to bottom: subjects 0012, 0102, 0106, 0121, 0130, and 0146. We note that the initial affine registration for subject 0102 (second row, second column) is incorrect; however our method managed to compensate and generate improved result compared to deformable mutual information registration.