Feasibility of Imaging Myelin Lesions in Multiple Sclerosis

Table 2

Tissue composition and target concentration in the modeled brain compartments.

	White matter	Gray matter	MS lesion
Mass fraction of brain (%)	42	56	2
Water fraction [21] (%)	72	82	76
Total protein; (% dry weight) [21]	39	55.3	31.7
Total protein; (% wet weight)	10.92	9.954	7.608
Total protein; (g/g wet weight)	109.2 × 10^−3	99.54 × 10^−3	76.08 × 10^−3
MBP; (mg/g protein)	172 [24]	25 [23]	87.8 [24]
MBP; (mg/g wet weight)	18.7824	2.4885	6.679824
MBP; (Molar concentration)	1.015 × 10^−3	1.345 × 10^−4	3.61 × 10^−4