Research Article

Detection of Melanoma Metastases in Resected Human Lymph Nodes by Noninvasive Multispectral Photoacoustic Imaging

Figure 1

(a) Photoacoustic image of phantom after illumination with 680 nm light. (b) Photoacoustic image of phantom after illumination with 840 nm light. (c) Relative position of the inclusions in (a), (b), and (f). (d) Measured spectra for the two regions indicated in (c) for five wavelengths before normalization. The curves represent average and error bars indicate standard deviation. (e) Reference spectra after per-pixel normalization. The curves represent average and the error bars indicate standard deviation. (f) Resemblance score for blood () and melanin () expressed as pseudocolors, hemoglobin in red and melanin in green.
163652.fig.001a
(a)
163652.fig.001b
(b)
163652.fig.001c
(c)
163652.fig.001d
(d)
163652.fig.001e
(e)
163652.fig.001f
(f)