Evaluation of Deformable Image Registration for Three-Dimensional Temporal Subtraction of Chest Computed Tomography Images

Figure 2

Sample output of the subtraction process and volume change tracker of Figure 1 after deformable image registration. The white arrows indicate the left lung lesion and right lung latent lesion. (a) Subtraction images were obtained by subtracting the warped moving images from the fixed images. (b), (c) Local enlarged subtraction images of the left lung lesion with six successive slices in the axial and coronal planes (showed clear enhanced shadows). (d), (e) Local enlarged images of lesion tissue with six successive slices and detailed comparisons of the morphological changes. In (d) and (e), the above row shows lesions in the warped moving images, while the below row shows lesions in the fixed images. No growth or shrinkage is noted. Perfectly fitted lesions are show in the two planes.

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