Classification of Alzheimer’s and MCI Patients from Semantically Parcelled PET Images: A Comparison between AV45 and FDG-PET

Table 2

Configuration of cost function and transformation model (rigid with 6 parameters versus affine with 12 parameters) of registration, comparing SPM and FLIRT tools based on landmark registration errors (LRE).

Configuration	Cost function	Transformation	LRE with SPM (mm)	LRE with FLIRT (mm)
	Mutual information	Rigid body	3.15 1.10	3.02 1.11
	Correlation ratio	Rigid body	2.26 0.92	2.13 0.86
	Mutual information	Affine	2.65 0.97	2.51 0.41
	Correlation ratio	Affine	1.12 0.45	0.98 0.31