Table of Contents Author Guidelines Submit a Manuscript
International Journal of Biomaterials
Volume 2009, Article ID 239643, 9 pages
http://dx.doi.org/10.1155/2009/239643
Research Article

Polycaprolactone Scaffolds Fabricated via Bioextrusion for Tissue Engineering Applications

1Department of Chemistry & Industrial Chemistry, University of Pisa, 56126 Pisa, Italy
2Center for Rapid and Sustainable Product Development, Polytechnic Institute of Leiria (IPL), 2414-016 Leiria, Portugal

Received 15 May 2009; Revised 22 June 2009; Accepted 23 June 2009

Academic Editor: Claudio Migliaresi

Copyright © 2009 Marco Domingos et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. P. J. Bártolo, H. Almeida, R. Rezende, T. Laoui, and B. Bidanda, “Advanced processes to fabricate scaffolds for tissue engineering,” in Virtual Prototyping & Bio Manufacturing in Medical Applications, B. Bidanda and P. J. Bártolo, Eds., Springer, New York, NY, USA, 2008. View at Google Scholar
  2. M. E. Hoque, W. Feng, Y. S. Wong et al., “Scaffolds designed and fabricated with elastic biomaterials applying CAD-CAM technique,” Tissue Engineering Part A, vol. 14, no. 5, p. 907, 2008. View at Google Scholar
  3. S. N. Rath, D. Cohn, and D. W. Hutmacher, “Comparison of chondrogenesis in static and dynamic environments using a SFF designed and fabricated PCL-PEO scaffold,” Virtual and Physical Prototyping, vol. 3, no. 4, pp. 209–219, 2008. View at Publisher · View at Google Scholar
  4. D. W. Hutmacher, “Scaffold design and fabrication technologies for engineering tissues—state of the art and future perspectives,” Journal of Biomaterials Science, Polymer Edition, vol. 12, no. 1, pp. 107–124, 2001. View at Publisher · View at Google Scholar
  5. J. Rouwkema, N. C. Rivron, and C. A. van Blitterswijk, “Vascularization in tissue engineering,” Trends in Biotechnology, vol. 26, no. 8, pp. 434–441, 2008. View at Publisher · View at Google Scholar
  6. V. Karageorgiou and D. Kaplan, “Porosity of 3D biomaterial scaffolds and osteogenesis,” Biomaterials, vol. 26, no. 27, pp. 5474–5491, 2005. View at Publisher · View at Google Scholar
  7. S. H. Oh, I. K. Park, J. M. Kim, and J. H. Lee, “In vitro and in vivo characteristics of PCL scaffolds with pore size gradient fabricated by a centrifugation method,” Biomaterials, vol. 28, no. 9, pp. 1664–1671, 2007. View at Publisher · View at Google Scholar
  8. I. Gibson, “Rapid prototyping: from product development to medicine and beyond,” Virtual and Physical Prototyping, vol. 1, no. 1, pp. 31–42, 2006. View at Google Scholar
  9. M. E. Hoque, Design and development of tissue engineering scaffolds using rapid prototyping technology, Ph.D. thesis, National University of Singapore, Singapore, 2007.
  10. L. Shor, S. Güçeri, X. Wen, M. Gandhi, and W. Sun, “Fabrication of three-dimensional polycaprolactone/hydroxyapatite tissue scaffolds and osteoblast-scaffold interactions in vitro,” Biomaterials, vol. 28, no. 35, pp. 5291–5297, 2007. View at Publisher · View at Google Scholar
  11. G. Vozzi, A. Rechichi, F. Dini et al., “PAM-microfabricated polyurethane scaffolds: in vivo and in vitro preliminary studies,” Macromolecular Bioscience, vol. 8, no. 1, pp. 60–68, 2008. View at Publisher · View at Google Scholar
  12. T. C. Lim, C. P. Bang, K. S. Chian, and K. F. Leong, “Development of cryogenic prototyping for tissue engineering,” Virtual and Physical Prototyping, vol. 3, no. 1, pp. 25–31, 2008. View at Publisher · View at Google Scholar
  13. D. W. Hutmacher, T. Schantz, I. Zein, K. W. Ng, S. H. Teoh, and K. C. Tan, “Mechanical properties and cell cultural response of polycaprolactone scaffolds designed and fabricated via fused deposition modeling,” Journal of Biomedical Materials Research, vol. 55, no. 2, pp. 203–216, 2001. View at Publisher · View at Google Scholar
  14. H. A. Almeida, C. Mota, A. Mateus, P. J. Bártolo, N. Ferreira, and M. Domingos, Portuguese Patent no. 104247, 2008.
  15. A. J. Mateus, H. A. Almeida, N. M. Ferreira et al., “Bioextrusion for tissue engineering applications,” in Virtual and rapid manufacturing, P. J. Bartolo, Ed., London, UK, Taylor & Francis, 2008. View at Google Scholar