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International Journal of Biomaterials
Volume 2009, Article ID 765813, 6 pages
Research Article

Adhesion of Respiratory-Infection-Associated Microorganisms on Degradable Thermoplastic Composites

1Department of Prosthetic Dentistry and Biomaterials Science, Institute of Dentistry, University of Turku, 20520 Turku, Finland
2Laboratory of Polymer Technology, Department of Chemical Technology, Helsinki University of Technology, 02150 Espoo, Finland
3Department of Otorhinolaryngology - Head and Neck Surgery, Turku University Central Hospital, Turku, 20520 Turku, Finland
4Clinic of Oral Diseases, Turku University Central Hospital, Turku, 20520 Turku, Finland

Received 5 October 2008; Accepted 3 March 2009

Academic Editor: Toshiki Miyazaki

Copyright © 2009 Teemu Tirri et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The purpose of this study was to evaluate bacterial adhesion and early colonization on a composite consisting of bioactive glass (BAG) particles and copolymer of -caprolactone/D,L-lactide. Materials were incubated with suspensions of both type strains and clinical isolates of Streptococcus pneumoniae, Haemophilus influenzae, and Pseudomonas aeruginosa for 30 minutes (adhesion) and 4 hours (colonization). Clear differences exist in the microorganisms' ability to adhere on the experimental materials. However, the presence of BAG particles does not inhibit bacterial adhesion, but early colonization of the materials with P. aeruginosa was inhibited by the addition of 90–315  m BAG particles.