Research Article

Nanoporosity of Alumina Surfaces Induces Different Patterns of Activation in Adhering Monocytes/Macrophages

Figure 4

SEM micrographs of monocytes/macrophages after 24 h of incubation on nanoporous alumina. MM on the 200 nm-pore membranes ((b) and (d)) show clear signs of activation (rough plasmalemma and extended filipodia), while cells on the 20 nm-pore membranes ((a) and (c)) appear more round shaped with little membrane ruffling and no established filipodia extensions. A higher tendency toward cell clustering and fusion was also observed on the 20 nm-pore alumina (c).
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(a)
402715.fig.004b
(b)
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(c)
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(d)