A New In Vivo Model System to Assess the Toxicity of Semiconductor Nanocrystals
Figure 3
Dose response toxicity curves to (a) TGA- and (b) GSH-capped QDs. 20 Hydra were treated with the indicated QD at increasing concentrations for 2 hours and then, following extensive washing, allowed to recover in physiological solution for 24 hr (blue line), 48 hr (red line), and, 72 hr (purple line), when morphology was appropriately scored. Median scores of morphological condition were compared by nonparametric Friedman Test; values with a letter in common are not significantly different (). The toxicity of TGA-and-GSH capped QDs on Hydra morphology increases with time and concentration.
