Perfusion Flow Enhances Osteogenic Gene Expression and the Infiltration of Osteoblasts and Endothelial Cells into Three-Dimensional Calcium Phosphate Scaffolds

Table 3

Changes in mRNA levels with perfusion flow at 7- and 14-day samples (osteoblast cultures).

Gene	7-day fold change	𝑃 value	14-day fold change	𝑃 value
ALP	↑142%	0.001	—	0.11
OCN	↑819%	0.02	—	0.91
RUNX-2	—	0.26	↓65%	0.01
VEGF	—	0.55	↓85%	<0.0001