Determination of Oxidative Stress Related Toxicity on Repeated Dermal Exposure of Hydroxyapatite Nanoparticles in Rats

Table 1

Experimental design.

Group	Dose	Number of rats		Exposure route	Days of exposure
		Male	Female
1	Control	5	5	Dermal	28
2	HANPs (25 mg/kg)	5	5	Dermal	28
3	HANPs (50 mg/kg)	5	5	Dermal	28
4	HANPs (100 mg/kg)	5	5	Dermal	28

HANPs: hydroxyapatite nanoparticles.