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International Journal of Biomaterials
Volume 2015 (2015), Article ID 165428, 6 pages
Research Article

Cyanoacrylate for Intraoral Wound Closure: A Possibility?

Department of Oral & Maxillofacial Surgery, Faculty of Dental Sciences, MSRUAS, MSRIT Post, MSR Nagar, Bangalore 560054, India

Received 24 July 2015; Revised 13 October 2015; Accepted 28 October 2015

Academic Editor: Ravin Narain

Copyright © 2015 Parimala Sagar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Wound closure is a part of any surgical procedure and the objective of laceration repair or incision closure is to approximate the edges of a wound so that natural healing process may occur. Over the years new biomaterials have been discovered as an alternate to conventional suture materials. Cyanoacrylate bioadhesives are one among them. They carry the advantages of rapid application, patient comfort, resistance to infection, hemostatic properties, and no suture removal anxiety. Hence this study was undertaken to study the effect of long chain cyanoacrylate as an adhesive for intraoral wound closure and also to explore its hemostatic and antibacterial effects. Isoamyl-2-cyanoacrylate (AMCRYLATE) was used as the adhesive in the study. In conclusion isoamyl cyanoacrylate can be used for intraoral wound closure, as an alternative to sutures for gluing the mucoperiosteum to bone, for example, after impaction removal, periapical surgeries, and cleft repair. Its hemostatic and antibacterial activity has to be further evaluated.