Novel Vanadium-Loaded Ordered Collagen Scaffold Promotes Osteochondral Differentiation of Bone Marrow Progenitor Cells

Figure 6

Biocompatibility of BMPC on and VOAsc-loaded scaffolds: : 10 μg/mL per cm² VOAsc; : 20 μg/mL per cm² VOAsc; and : 40 μg/mL per cm² VOAsc. Cells were plated on different collagen membranes and adhesion (1 h (a)) and proliferation (24 h (b)) were evaluated by Giemsa staining. Cells in 10 representative fields per sample were counted and averaged. BMPC growing on different membranes were induced to be differentiated in osteogenic media: ALP (15 days (c)) or mineralization (21 days (d)) or chondrogenic media, GAG production (21 days (e)). Results are expressed as % of basal (cells differentiated in the film) and they are expressed as mean ± SEM. ; ; .

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