Silver Nanoparticles: Biosynthesis Using an ATCC Reference Strain of Pseudomonas aeruginosa and Activity as Broad Spectrum Clinical Antibacterial Agents
Table 1
Minimum inhibitory concentration (MIC) of Ag-NPs and ciprofloxacin and minimum bactericidal concentration (MBC) of Ag-NPs for different bacterial species.
Bacterial strain
Ag-NPs
Ciprofloxacin
MIC (pM)
MBC (pM)
MBC/MIC
MIC (μM)
Gram-positive bacteria
S. aureus ATCC 29213
0.8
0.8
1.0
1.6
MSSA clinical strain 1
0.8
0.8
1.0
0.8
MSSA clinical strain 2
0.4
0.4
1.0
0.8
MSSA clinical strain 3
0.4
0.8
2.0
0.4
MRSA clinical strain
3.2
3.2
1.0
99.1
S. epidermidis ATCC 12228
3.2
6.2
1.9
3.1
E. faecalis ATCC 29212
0.8
0.8
1.0
0.8
Gram-negative bacteria
P. mirabilis clinical strain
0.4
0.4
1.0
0.4
A. baumannii clinical strain
0.8
0.8
1.0
1.6
E. coli ATCC 25922
1.6
3.2
2.0
0.4
E. coli clinical strain 1
1.6
1.6
1.0
0.8
E. coli clinical strain 2
3.2
3.2
1.0
1.0
P. aeruginosa ATCC 27853
6.4
6.4
1.0
3.1
K. pneumoniae ATCC 700603
0.8
1.6
2.0
0.4
MSSA: methicillin-sensitive S. aureus; MRSA: methicillin-resistant S. aureus.
