Oxidative Nanopatterning of Titanium Surface Influences mRNA and MicroRNA Expression in Human Alveolar Bone Osteoblastic Cells

Table 4

Relative expression levels of mRNAs differentially expressed among control (C), nanotexture (N), nano+submicrotexture (NS), and rough microtexture (MR) groups after 10 days of culture. FC: fold change.

Gene	C versus MR	C versus S	C versus N	MR versus NS	MR versus N	NS versus N
	FC	FC	FC	FC	FC	FC
ABCB9	2,423	1,045	1,106	−2,319	−2,191	1,059
AIPL1	1,055	−2,369	1,164	−2,500	1,103	2,758
AMICA1	2,308	1,693	2,524	−1,364	1,094	1,491
ATP6V0A4	−5,137	−1,532	−3,833	3,353	1,340	−2,502
BTK	−4,130	−1,516	−6,530	2,725	−1,581	−4,308
C10orf27	−2,049	−1,277	−1,827	1,605	1,122	−1,431
CD28	−3,104	−1,478	−2,068	2,101	1,501	−1,400
CDX1	−2,178	−1,136	−1,572	1,918	1,386	−1,384
CENPF	2,296	1,639	1,574	−1,401	−1,459	−1,041
COL24A1	2,308	1,076	−1,584	−2,144	−3,655	−1,705
CYP27B1	2,325	−1,042	4,278	−2,422	1,840	4,457
E2F5	2,572	1,012	3,240	−2,542	1,260	3,203
EPB41L5	2,725	1,796	2,440	−1,518	−1,117	1,359
ERBB3	−2,036	1,391	−1,934	2,832	1,052	−2,691
FGF1	1,929	1,309	2,792	−1,473	1,447	2,132
GPAM	3,438	−1,467	2,420	−5,045	−1,421	3,551
GRIN2A	2,065	−1,066	2,005	−2,202	−1,030	2,138
HSF4	−2,358	−2,213	−1,331	1,066	1,772	1,663
KDR	1,563	−1,134	2,118	−1,772	1,355	2,401
KIAA1109	1,948	1,340	2,146	−1,453	1,102	1,602
LAMC3	2,138	2,921	2,086	1,366	−1,025	−1,400
LGI1	3,533	1,452	4,124	−2,433	1,167	2,839
LUC7L3	2,064	1,673	1,507	−1,234	−1,370	−1,110
MAPT	6,567	1,653	4,711	−3,973	−1,394	2,849
MECOM	−2,952	−3,421	−8,666	−1,159	−2,936	−2,533
MMP7	2,731	1,120	2,208	−2,438	−1,237	1,972
NANOG	3,365	2,137	3,791	−1,575	1,127	1,774
NCKAP1L	−1,722	−2,257	−1,736	−1,311	−1,008	1,300
NOTCH1	1,306	−1,812	1,416	−2,367	1,084	2,565
NRXN1	2,462	1,377	−1,203	−1,788	−2,963	−1,657
PCDHA11	2,074	−1,266	2,259	−2,626	1,089	2,859
PCDHB10	3,328	−1,025	3,581	−3,411	1,076	3,669
PDE3A	−3,260	1,121	−3,908	3,656	−1,199	−4,382
PHOSPHO1	−2,024	−1,214	−1,757	1,667	1,152	−1,448
PSMD3	−2,075	−2,131	−1,353	−1,027	1,533	1,574
PTPRC	1,453	−1,392	1,475	−2,022	1,016	2,054
PTPRK	−3,909	−1,952	1,034	2,002	4,040	2,018
RNF7	2,803	1,199	1,387	−2,339	−2,021	1,157
SMURF2	1,193	−2,344	−1,142	−2,797	−1,362	2,053
SORBS1	−3,880	−3,008	−3,342	1,290	1,161	−1,111
SOX21	2,006	1,583	2,829	−1,267	1,411	1,787
UTRN	−1,602	−1,884	−2,062	−1,176	−1,287	−1,094