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International Journal of Biomaterials
Volume 2017, Article ID 1256537, 11 pages
Research Article

Effect of Injection Molding Melt Temperatures on PLGA Craniofacial Plate Properties during In Vitro Degradation

1LEBm Biomechanics Engineering Laboratory, University Hospital (HU), Federal University of Santa Catarina, 88040-900 Florianópolis, SC, Brazil
2NIMMA Laboratory of Innovation on Additive Manufacturing and Molding, Federal University of Santa Catarina, 88040-900 Florianópolis, SC, Brazil
3GRANTE, Department of Mechanical Engineering, Federal University of Santa Catarina, 88040-900 Florianópolis, SC, Brazil

Correspondence should be addressed to Liliane Pimenta de Melo; moc.liamg@gne.enailil

Received 10 June 2017; Revised 24 July 2017; Accepted 30 July 2017; Published 6 September 2017

Academic Editor: Junling Guo

Copyright © 2017 Liliane Pimenta de Melo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The purpose of this article is to present mechanical and physicochemical properties during in vitro degradation of PLGA material as craniofacial plates based on different values of injection molded temperatures. Injection molded plates were submitted to in vitro degradation in a thermostat bath at 37 ± 1°C by 16 weeks. The material was removed after 15, 30, 60, and 120 days; then bending stiffness, crystallinity, molecular weights, and viscoelasticity were studied. A significant decrease of molecular weight and mechanical properties over time and a difference in FT-IR after 60 days showed faster degradation of the material in the geometry studied. DSC analysis confirmed that the crystallization occurred, especially in higher melt temperature condition. DMA analysis suggests a greater contribution of the viscous component of higher temperature than lower temperature in thermomechanical behavior. The results suggest that physical-mechanical properties of PLGA plates among degradation differ per injection molding temperatures.