Application of Synthetic Polymeric Scaffolds in Breast Cancer 3D Tissue Cultures and Animal Tumor Models

Figure 2

Type I collagen and integrin 2 receptor expression in breast epithelial cells cultured on PLGA-coated surfaces. The expression and deposition of type I collagen (green) as well as its cell surface receptor integrin 2 (red) expression was inspected in MCF10A and MDA-MB-231 cells grown on the PLGA-coated glass slides using IF staining couple with confocal microscopy. The nuclei of the cells were stained with DAPI (Blue). Scale bars, 10 m.