Review Article
Strain and Vibration in Mesenchymal Stem Cells
Table 2
Effect of cyclic tensile strain on MSCs seeded on 2D scaffolds.
| Scaffold | Cell | Strain (%) | Time (hrs) | Differentiation | Ref. |
| 2D Natural | Collagen | hMSCs | 5 | 24 | Myogenic | [19] | hMSCs | 10 | 24 | Myogenic | [20] | hMSCs | 3, 10 | 8, 48 | Tenogenic (10%) | [21] | hMSCs | 0.8, 5, 10, 15 | 48 | Osteogenesis (<5%) Osteogenic inhibition (>5%) | [22] |
| 2D Natural + synthetic | Elastin | hMSCs | 10 | 24 | Myogenic | [20] | Silicone | rMSCs | 10 | N/A | Tenogenic | [23] | Elastin-silicone | rMSCs | 5, 10, 15, 20 | 24 | Myogenic (10%) | [24] | Elastin-silicone | rMSCs | 10 | 24, 48, 72 | Myogenic | [24] |
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Myogenic expression transiently increased; expression reduced to basal levels after cell alignment.
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