Nonirritant and Cytocompatible Tinospora cordifolia Nanoparticles for Topical Antioxidant Treatments

Table 5

Evaluation scale of dermal reactions (erythema and edema).

Erythema formation	Value	Edema formation	Value
No presence of erythema	0	No edema formation	0
Very slight erythema (almost imperceptible)	1	Very slight edema (almost imperceptible)	1
Well-defined erythema	2	Light edema (well-defined area with significant elevation)	2
Moderate-to-severe erythema	3	Moderate edema (elevation of approximately 1 mm)	3
Severe erythema (red beet) with formation of scabs (deep lesions)	4	Severe edema (elevation greater than 1 mm and extending beyond the exposure area)	4
Maximum possible	4	Maximum possible	4